The master plan consists of 12 building blocks with a diverse programme with dwellings, (care) facilities, and offices. By breaking open the closed design of the existing Kruisgebouw (cross building) , four green courtyards are created that connect the complex with the surrounding city. The area will once again become an open and dynamic part of the city, and the accessibility between CVZ Slotervaart and the surrounding neighbourhoods will be improved.
The Kruisgebouw, built in 1975, forms the starting point for the vision and will become the beating heart of CVZ. The lower floors will facilitate various health care functions and on the upper floors several care homes will be created. The space around the building will be used as a new living and working area. An additional 80,000 m2 will be built here, creating a highly urban mixed neighbourhood with a high building density that is in line with developments in the immediate vicinity. CVZ is part of a cluster called De Plantijn sub-area. In addition to the former Slotervaart Medical Center, the Antoni van Leeuwenhoek Hospital, the Nederlands Cancer Institute, Sanquin and the Hof van Sloten care home are housed here.